Sunday, 9 November 2014

Drug Therapy for Type 2 Diabetes

It is estimated that there are nearly 350 million adults with diabetes. Type 2 diabetes accounts for over 90% of this burden. The International Diabetes Federation (IDF) estimates that diabetes resulted in almost 4 million deaths in 2007. The World Health Organization (WHO) estimates that the number of people affected worldwide will grow to more than 470 million by 2030, the majority in low to middle-income countries. A powerful dose association exists between obesity and the risk of developing type 2 diabetes (Figure 1.1). The WHO estimates that more than 1 billion adults are over their ideal body weight, at least 300 million of them being clinically obese. The prevention of type 2 diabetes is a pressing public health issue. Translating the results of studies that have shown that intensive lifestyle measures i.e. weight reduction and increased levels of physical activity, can avert or postpone progression to diabetes is a formidable challenge.